Mydriasis (Dilated Pupils)
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When it is dark a cat’s pupils dilate to allow more light to reach the retina to provide better vision. When a cat is nervous his pupils will also dilate. These normal functions of the eye are the result of the nerves in the eye communicating information to the brain.  The message is sent through the nerves to the iris which dilates or constricts the pupil.

 

When there are disruptions in this pathway the pupil will not respond normally to light. Mydriasis is the excessive dilation of the pupil due to disease, trauma or medication. Ophthalmic and neurologic examinations along with specific testing are needed to find the cause of this abnormality. Blood pressure, intraocular pressure and feline leukemia testing are among the first diagnostics needed.  The prognosis varies from excellent to grave and treatment is based on the specific diagnosis. Below are some of the causes of mydriasis.

 

Mydriasis with vision defects

This occurs when there is damage to the retina, optic nerve, optic chiasm or the optic tract.  If only one eye is damaged the dilation may be mild in the affected eye. If both eyes are involved the dilation of the pupil is much more noticeable.

 

1.   Hypertension, intraocular hemorrhage (most common)

2. Infectious disease (Toxoplasmosis, Panleukopenia, FIP, FeLV, FIV, Histoplasmosis, Cryptococcosis)

3.   Glaucoma

4.   Neoplasia- such as lymphosarcoma

5.   Progressive retinal atrophy

6.   Toxic insult to the retina producing retinal degeneration (example-enrofloxacin)

7.   Trauma

8.   Central retinal degeneration- inadequate taurine levels 

 

Mydriasis with normal vision

1.     Medications

a.      Atropine, tropicamide

b.     Anesthetic agents (example-ketamine)

c.      Opioids (buprenorphine) dilates pupils in cats but not dogs

2.     Trauma or tumors involving the brain or nerves

3.     Dysautonomia-  generalized disease of autonomic nerves

4.     Hepatic encephalopathy

 

Dilated pupils are an important clinical sign of disease and investigation into the cause is essential. Many times the patient is suffering from a systemic disease and this is the first clue that the patient needs attention.

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